题目：Chemoselective Synthesis of Unsymmetrical Dithioacetals through Sequential Carbene Insertion and Acetal Exchange of Acylsilanes and Thiols under Visible Light Irradiation

作者：Wang Zhang, Dan-Ni Yang, Dou-Dou Guo, Peng Wang*, and Man-Yi Han*

单位：Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education, College of Chemistry and Materials Science, Huaibei Normal University, Huaibei, Anhui 235000, P.R. China

摘要：Dithioacetals are a frequently used motif in synthetic organic chemistry, and most existing reports discuss only symmetrical dithioacetals. Examples of unsymmetrical dithioacetals are scarce, and few general methods for the selective synthesis of these compounds exists. An intriguing visible-light-induced strategy has been established in this work for sequential reactions of S–H insertion and acetal exchange between acylsilanes and two different thiols that deliver a wide variety of unsymmetrical dithioacetals in moderate yields. The unsymmetrical dithioacetals were obtained with high selectivity, and a great variety of functional groups were tolerated.

影响因子：5.2

分区情况：一区

链接：https://pubs.acs.org/doi/10.1021/acs.orglett.4c00133

                        （文：汪鹏 / 审核：李洪基 / 审校：韩满意 / 终审：韩满意）